DNA polymerase activity in muscle cultures

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DNA polymerase activity in muscle cultures

Nuclei within myotubes do not synthesize DNA for replication. Accordingly, cultures of myotubes display low levels of DNA polymerase activity. The coincidental decline in DNA polymerase activity and increased formation of multinucleated myotubes during culture does not prove that the loss of capacity to synthesize DNA is a consequence of fusion. Tne experiments described demonstrate that myogen...

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ژورنال

عنوان ژورنال: Journal of Cell Biology

سال: 1978

ISSN: 0021-9525,1540-8140

DOI: 10.1083/jcb.77.1.99